Objective: The study compared psychological states and well-being between people with acute coronary syndromes (ACS) and their healthy counterpart. Methods: 85 ACS patients (UA: 56, NSTEMI: 15, STEMI: 14; aged 52.6±10.2 years; 20% women) and 63 healthy counterparts (aged 48.7±6.7; 39.7% women) were recruited for this study. Measures for psychological states included depression, anxiety, stress and hostility, in which group differences were reported in previous studies. Also health-related quality of life (HRQoL) and life satisfaction were measured to investigate positive aspects of their psychological well-being. Multivariate analysis was conducted. Results: No significant group differences were found in psychological states between people with ACS and their healthy counterparts. However, ACS group reported lower physical health on HRQoL and higher life satisfaction than healthy group. These results suggest that ACS patients have worse quality of psychological well-being, but they have no problem with psychological states. Psychological well-being may be associated with ACS.